Annual Conference on Drug Discovery 2020 | Drug Discovery Meetings

Symposium I: "Infectious Disease Therapeutics and Nucleic Acids-Based Therapeutics"

Chair: Dean Tang, Ph.D.

CO-CHAIRMAN: Ryan Bennett, Ph.D.

Sterghios A. Moschos, FRSC FIBMS FHEA MRSB

Northumbria University, UK

Title: Resolving Cytosolic Molecular Therapy for Airways Disease

Dean Tang, Ph.D.

Director, the ET Graduate Program, Roswell Park Comprehensive Cancer Center, Buffalo, NY

Title: TBA

Xiaodong Cheng, Ph.D.

Professor, Department of Integrative Biology & Pharmacology, University of Texas Health Science Center at Houston, Houston, TX

Title: Novel therapeutic strategy targeting pathogen-host interaction

Ryan Bennett, Ph.D.

Chief Scientific Officer, OyaGen, Inc., Rochester, NY

Title: A small molecule therapeutics for COVID-19

Gene D. Morse, PharmD, BCPS, FCCP

University at Buffalo, Buffalo, New York

Title: Translational pharmacology considerations for HIV-1 broadly neutralizing antibodies

Benjamin L. Miller, Ph.D.

Dean’s Professor of Dermatology, University of Rochester Medical Center, Rochester, NY

Title: Strategies for Targeting Viral RNA with Synthetic Molecules

Jack M. Sullivan, Ph.D.

Jacobs School of Medicine & Biomedical Sciences, Buffalo, NY

Title: Hammerhead ribozymes with protein-level catalytic rates- revitalizing a post-transcriptional modality for therapeutic RNA drug discovery

Upinder Singh, M.D.

Chief, Infectious Diseases & Geographic Medicine, Stanford University, Stanford, CA

Title: Drug discovery for parasitic amebae

Ramana V. Davuluri, Ph.D.

Northwestern University - Feinberg School of Medicine, Chicago, IL

Title: Transitioning Novel MerTK Small Molecule Inhibitors into Oncology Clinical Trials

Jian Zhu, Ph.D.

Associate Professor, Department of Pathology, Ohio State University College of Medicine Columbus, OH

Title: Role of m5C RNA methylation in regulating HIV infection

Symposium II: "Medicinal Chemistry and Enabling Technologies"

Chair: Guillermo A. Morales, Ph.D., MBA

CO-CHAIRMAN: David H. Thompson, Ph.D.

Larry Sklar, Ph.D.

Director, UNM Center for Molecular Discovery, NM

Title: Two Decades of High Throughput Flow Cytometry for Drug Discovery and Repurposing at the University of New Mexico Center for Molecular Discovery

David H. Thompson, Ph.D.

Professor, Department of Chemistry, Purdue University, West Lafayette, IN

Title: Immunostimulatory response of bladder tumor cells treated with RWFV peptide-targeted lipid nanoparticle

Guillermo A. Morales, Ph.D., MBA

CEO, Innoventyx, Oro Valley, Arizona

Title: Unconventional innovation, strategic insights, and unprecedented initiatives for the discovery, design, and development of novel drugs

Lisa A. Delouise, Ph.D., M.P.D

Associate Professor, University of Rochester Medical Center, Rochester, NY

Title: Microbubble Arrays: A Platform Technology for High-throughput Screening of Single Cells and Tissues

Paul C. Trippier, Ph.D.

Associate Professor, Department of Pharmaceutical Sciences, University of Nebraska Medical Center Omaha, NE

Title: Multi-functional Small Molecules for Drug Discovery in CLN3 Disease

Stephen A. Duncan, Ph.D.

Medical University of South Carolina, Charleston, SC

Title: Using iPSC-derived Hepatocytes as a Platform to Identity Treatments for Metabolic Liver Disease

Danielle S.W. Benoit, Ph.D.

Director, Materials Science Program, University of Rochester, Rochester, NY

Title: Salivary gland microphysiological systems for drug screening

Marton Toth, Ph.D.

Business Development Manager, NemaLife Inc., st., Lubbock, TX

Title: Integrating genetic diversity and drug-drug interaction testing in early drug discovery

Elysia Masters

University of Rochester, Rochester, NY

Title: A Preclinical Drug Discovery Platform for Novel Antibiotics to Treat Bone Infections

Soon Gang Choi, Ph.D.

Research Fellow, Harvard Medical School, Boston, MA

Title: Druggability of the protein interactome: High-throughput discovery of chemical modulators of protein-protein interactions

Yuwei Wang, Ph.D.

California Health Sciences University, CA

Title: Application of A Quality by Design Approach (QbD) for Liposomal Drug Lyophilization Process Development

Symposium-III: "Cannabinoids, Terpenes in Medicinal Regulation of the Endocannabinoid System"

Chair: Bernd Markus-Lange, Ph.D.

CO-CHAIRMAN: Klaus Gawrisch, Ph.D.

Dvora Namdar, Ph.D.

Senior Research Fellow, Institute of Plant Sciences, ARO, Volcani Center, Israel

Title: Cannabis phytomolecules: from domestication to medicalization, from ‘entourage’ to ‘parasitage’, from antiquity to day

Lakshmi P. Kotra, Ph.D.

Professor, University of Toronto, and Senior Scientist, University Health Network, Toronto, ON, Canada

Title: Bedside to Bud: Tying the Patient to Medicine

Bernd Markus-Lange, Ph.D.

Washington State University, Pullman, WA

Title: Beyond the High: Intertwined Biochemical Pathways Toward Cannabinoids and Aroma Terpenoids in Cannabis

Eilis Dowd, Ph.D.

Senior Lecturer in Pharmacology, National University of Ireland, Galway, Ireland

Title: Neuroinflammation in Parkinson’s, and the Therapeutic Potential of Cannabinoids.

Klaus Gawrisch, Ph.D.

Chief, Section of NMR, Chief, Laboratory of Membrane Biochemistry and Biophysics, NIAAA, NIH, Bethesda, MD

Title: Activation of cannabinoid receptors by the endogenous ligand 2-AG

István Katona, Ph.D.

Naus Family Chair in Addiction Sciences, Indiana University, Bloomington/Institute of Experimental Medicine, Budapest, Hungary

Title: Super-resolution imaging reveals cell-type-specific molecular tolerance to THC

David A. Scott, Ph.D.

University of Louisville School of Dentistry, Louisville, KY

Title: Phytocannabinoids suppress the innate immune response to bacterial challenge

Malliga R. Iyer, Ph.D.

Staff Scientist, Director of Medicinal Chemistry Core, NIAAA/NIH, Rockville, MD

Title: Cannabinoid Receptor-based Polypharmacological Approaches to treat Metabolic and Fibrotic Disorders

Paul J. Kenny, Ph.D.

Icahn School of Medicine at Mount Sinai, New York City, NY

Title: Development of orexin receptor antagonists for the treatment of drug addiction

Steven Laviolette, Ph.D.

University of Western Ontario, Ontario, Canada

Title: Understanding the Mechanisms of Cannabidiol for the Treatment of Mental Health Disorders

Christopher W. Cunningham, Ph.D.

Director, Center for Structure-Based Drug Design & Development, Mequon, WI

Title: Endocannabinoid Transport Inhibitors as Novel Anxiolytics

Daniel Lantela

Co-Founder and Director of Drug Development, Whistler Therapeutics, BC, Canada

Title: TBA

Jacob Toth, Ph.D.

School of Integrative Plant Science, Plant Breeding and Genetics Section, Cornell University, NY

Title: Variation between and within high-cannabinoid hemp cultivars

Andrew Kesner, Ph.D.

Postdoctoral Fellow, NIH Center on Compulsive Behaviors, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD

Title: Modeling spontaneous THC withdrawal symptoms in mice

Symposium -IV: "Preclinical Drug Discovery for Novel Oncology Therapeutics"

Chair: Ergün Sahin, M.D, Ph.D.

CO-CHAIRMAN: Arthur M. Edelman, Ph.D.

Andrei V. Gudkov, Ph.D.

Roswell Park Comprehensive Cancer Center and Genome Protection, Inc., Buffalo, NY

Title: Development of TLR5 agonists for radioprotective, anticancer and antiaging applications

Gokul M. Das, Ph.D.

Associate Professor, Roswell Park Comprehensive Cancer Center, Buffalo, NY

Title: Drug Repurposing to Target Estrogen Receptor-beta and p53 Interaction: A Novel Therapeutic Strategy against Triple Negative Breast Cancer

Thomas E. Smithgall, Ph.D.

Chair, Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA

Title: Drug Discovery Targeting Src-family Kinases in Acute Myeloid Leukemia

Chandra Bartholomeusz, Ph.D.

Associate Professor, The University of Texas MD Anderson Cancer Center, Houston, TX

Title: MAPK signaling pathway: an emerging player in TNBC

Arthur M. Edelman, Ph.D.

Associate Professor, University at Buffalo, State University of New York, NY

Title: Kinases and Cancer, the Curious Case of CaMKK2

Dhyan Chandra, Ph.D.

Associate Professor, Roswell Park Comprehensive Cancer Center, Buffalo, NY

Title: Mitochondrial Dysfunction in Cancer

Xinjiang Wang, Ph.D.

Associate Professor, Dept. of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY

Title: TBA

Belgin Sever, Ph.D.

Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Anadolu University, Turkey

Title: New 1,3,4-Oxadiazole Derivatives as Apoptosis Inducers and EGFR Inhibitors

John J. Seman, Ph.D.

Canget BioTekpharma LLC., Buffalo, NY

Title: Novel portfolio of cancer drugs eliminate tumors and overcome multiple mechanisms of drug resistance

Speakers

Symposia

Chair: Dean Tang, Ph.D.

CO-CHAIRMAN: Ryan Bennett, Ph.D.

Chair: Guillermo A. Morales, Ph.D., MBA

CO-CHAIRMAN: David H. Thompson, Ph.D.

Chair: Bernd Markus-Lange, Ph.D.

CO-CHAIRMAN: Klaus Gawrisch, Ph.D.

Chair: Ergün Sahin, M.D, Ph.D.

CO-CHAIRMAN: Arthur M. Edelman, Ph.D.

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