Symposium I: "Infectious Disease Therapeutics and Nucleic Acids-Based Therapeutics"

Chair: Dean Tang, Ph.D.

     CO-CHAIRMAN: Ryan Bennett, Ph.D.

Sterghios A. Moschos
Sterghios A. Moschos, FRSC FIBMS FHEA MRSB
Northumbria University, UK
Title: Resolving Cytosolic Molecular Therapy for Airways Disease
Dean Tang
Dean Tang, Ph.D.
Director, the ET Graduate Program, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: TBA
Xiaodong Cheng
Xiaodong Cheng, Ph.D.
Professor, Department of Integrative Biology & Pharmacology, University of Texas Health Science Center at Houston, Houston, TX
Title: Novel therapeutic strategy targeting pathogen-host interaction
Ryan Bennett
Ryan Bennett, Ph.D.
Chief Scientific Officer, OyaGen, Inc., Rochester, NY
Title: A small molecule therapeutics for COVID-19
Gene D. Morse
Gene D. Morse, PharmD, BCPS, FCCP
University at Buffalo, Buffalo, New York
Title: Translational pharmacology considerations for HIV-1 broadly neutralizing antibodies
Benjamin L. Miller
Benjamin L. Miller, Ph.D.
Dean’s Professor of Dermatology, University of Rochester Medical Center, Rochester, NY
Title: Strategies for Targeting Viral RNA with Synthetic Molecules
Jack M. Sullivan
Jack M. Sullivan, Ph.D.
Jacobs School of Medicine & Biomedical Sciences, Buffalo, NY
Title: Hammerhead ribozymes with protein-level catalytic rates- revitalizing a post-transcriptional modality for therapeutic RNA drug discovery
Upinder Singh
Upinder Singh, M.D.
Chief, Infectious Diseases & Geographic Medicine, Stanford University, Stanford, CA
Title: Drug discovery for parasitic amebae
Ramana V. Davuluri
Ramana V. Davuluri, Ph.D.
Northwestern University - Feinberg School of Medicine, Chicago, IL
Title: Transitioning Novel MerTK Small Molecule Inhibitors into Oncology Clinical Trials
Jian Zhu
Jian Zhu, Ph.D.
Associate Professor, Department of Pathology, Ohio State University College of Medicine Columbus, OH
Title: Role of m5C RNA methylation in regulating HIV infection

Symposium II: "Medicinal Chemistry and Enabling Technologies"

Chair: Guillermo A. Morales, Ph.D., MBA

     CO-CHAIRMAN: David H. Thompson, Ph.D.

Larry Sklar
Larry Sklar, Ph.D.
Director, UNM Center for Molecular Discovery, NM
Title: Two Decades of High Throughput Flow Cytometry for Drug Discovery and Repurposing at the University of New Mexico Center for Molecular Discovery
David H. Thompson
David H. Thompson, Ph.D.
Professor, Department of Chemistry, Purdue University, West Lafayette, IN
Title: Immunostimulatory response of bladder tumor cells treated with RWFV peptide-targeted lipid nanoparticle
Guillermo A. Morales
Guillermo A. Morales, Ph.D., MBA
CEO, Innoventyx, Oro Valley, Arizona
Title: Unconventional innovation, strategic insights, and unprecedented initiatives for the discovery, design, and development of novel drugs
Lisa A. Delouise
Lisa A. Delouise, Ph.D., M.P.D
Associate Professor, University of Rochester Medical Center, Rochester, NY
Title: Microbubble Arrays: A Platform Technology for High-throughput Screening of Single Cells and Tissues
Paul C. Trippier
Paul C. Trippier, Ph.D.
Associate Professor, Department of Pharmaceutical Sciences, University of Nebraska Medical Center Omaha, NE
Title: Multi-functional Small Molecules for Drug Discovery in CLN3 Disease
Stephen A. Duncan
Stephen A. Duncan, Ph.D.
Medical University of South Carolina, Charleston, SC
Title: Using iPSC-derived Hepatocytes as a Platform to Identity Treatments for Metabolic Liver Disease
Danielle S.W. Benoit
Danielle S.W. Benoit, Ph.D.
Director, Materials Science Program, University of Rochester, Rochester, NY
Title: Salivary gland microphysiological systems for drug screening
Marton Toth
Marton Toth, Ph.D.
Business Development Manager, NemaLife Inc., st., Lubbock, TX
Title: Integrating genetic diversity and drug-drug interaction testing in early drug discovery
Elysia Masters
Elysia Masters
University of Rochester, Rochester, NY
Title: A Preclinical Drug Discovery Platform for Novel Antibiotics to Treat Bone Infections
Soon Gang Choi
Soon Gang Choi, Ph.D.
Research Fellow, Harvard Medical School, Boston, MA
Title: Druggability of the protein interactome: High-throughput discovery of chemical modulators of protein-protein interactions
Yuwei Wang
Yuwei Wang, Ph.D.
California Health Sciences University, CA
Title: Application of A Quality by Design Approach (QbD) for Liposomal Drug Lyophilization Process Development

Symposium-III: "Cannabinoids, Terpenes in Medicinal Regulation of the Endocannabinoid System"

Chair: Bernd Markus-Lange, Ph.D.

     CO-CHAIRMAN: Klaus Gawrisch, Ph.D.

Elmar Nurmemmedov
Dvora Namdar, Ph.D.
Senior Research Fellow, Institute of Plant Sciences, ARO, Volcani Center, Israel
Title: Cannabis phytomolecules: from domestication to medicalization, from ‘entourage’ to ‘parasitage’, from antiquity to day
Lakshmi P. Kotra
Lakshmi P. Kotra, Ph.D.
Professor, University of Toronto, and Senior Scientist, University Health Network, Toronto, ON, Canada
Title: Bedside to Bud: Tying the Patient to Medicine
Bernd Markus-Lange
Bernd Markus-Lange, Ph.D.
Washington State University, Pullman, WA
Title: Beyond the High: Intertwined Biochemical Pathways Toward Cannabinoids and Aroma Terpenoids in Cannabis
Eilis Dowd
Eilis Dowd, Ph.D.
Senior Lecturer in Pharmacology, National University of Ireland, Galway, Ireland
Title: Neuroinflammation in Parkinson’s, and the Therapeutic Potential of Cannabinoids.
Klaus Gawrisch
Klaus Gawrisch, Ph.D.
Chief, Section of NMR, Chief, Laboratory of Membrane Biochemistry and Biophysics, NIAAA, NIH, Bethesda, MD
Title: Activation of cannabinoid receptors by the endogenous ligand 2-AG
István Katona
István Katona, Ph.D.
Naus Family Chair in Addiction Sciences, Indiana University, Bloomington/Institute of Experimental Medicine, Budapest, Hungary
Title: Super-resolution imaging reveals cell-type-specific molecular tolerance to THC
David A. Scott
David A. Scott, Ph.D.
University of Louisville School of Dentistry, Louisville, KY
Title: Phytocannabinoids suppress the innate immune response to bacterial challenge
Malliga R. Iyer
Malliga R. Iyer, Ph.D.
Staff Scientist, Director of Medicinal Chemistry Core, NIAAA/NIH, Rockville, MD
Title: Cannabinoid Receptor-based Polypharmacological Approaches to treat Metabolic and Fibrotic Disorders
Paul J. Kenny
Paul J. Kenny, Ph.D.
Icahn School of Medicine at Mount Sinai, New York City, NY
Title: Development of orexin receptor antagonists for the treatment of drug addiction
Steven Laviolette
Steven Laviolette, Ph.D.
University of Western Ontario, Ontario, Canada
Title: Understanding the Mechanisms of Cannabidiol for the Treatment of Mental Health Disorders
Christopher W. Cunningham
Christopher W. Cunningham, Ph.D.
Director, Center for Structure-Based Drug Design & Development, Mequon, WI
Title: Endocannabinoid Transport Inhibitors as Novel Anxiolytics
Daniel Lantela
Daniel Lantela
Co-Founder and Director of Drug Development, Whistler Therapeutics, BC, Canada
Title: TBA
Jacob Toth
Jacob Toth, Ph.D.
School of Integrative Plant Science, Plant Breeding and Genetics Section, Cornell University, NY
Title: Variation between and within high-cannabinoid hemp cultivars
Andrew Kesner
Andrew Kesner, Ph.D.
Postdoctoral Fellow, NIH Center on Compulsive Behaviors, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD
Title: Modeling spontaneous THC withdrawal symptoms in mice

Symposium -IV: "Preclinical Drug Discovery for Novel Oncology Therapeutics"

Chair: Ergün Sahin, M.D, Ph.D.

     CO-CHAIRMAN: Arthur M. Edelman, Ph.D.

Andrei V. Gudkov
Andrei V. Gudkov, Ph.D.
Roswell Park Comprehensive Cancer Center and Genome Protection, Inc., Buffalo, NY
Title: Development of TLR5 agonists for radioprotective, anticancer and antiaging applications
Gokul M. Das
Gokul M. Das, Ph.D.
Associate Professor, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: Drug Repurposing to Target Estrogen Receptor-beta and p53 Interaction: A Novel Therapeutic Strategy against Triple Negative Breast Cancer
Thomas E. Smithgall
Thomas E. Smithgall, Ph.D.
Chair, Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA
Title: Drug Discovery Targeting Src-family Kinases in Acute Myeloid Leukemia
Chandra Bartholomeusz
Chandra Bartholomeusz, Ph.D.
Associate Professor, The University of Texas MD Anderson Cancer Center, Houston, TX
Title: MAPK signaling pathway: an emerging player in TNBC
Arthur M. Edelman
Arthur M. Edelman, Ph.D.
Associate Professor, University at Buffalo, State University of New York, NY
Title: Kinases and Cancer, the Curious Case of CaMKK2
Dhyan Chandra
Dhyan Chandra, Ph.D.
Associate Professor, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: Mitochondrial Dysfunction in Cancer
Xinjiang Wang
Xinjiang Wang, Ph.D.
Associate Professor, Dept. of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: TBA
Belgin Sever
Belgin Sever, Ph.D.
Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Anadolu University, Turkey
Title: New 1,3,4-Oxadiazole Derivatives as Apoptosis Inducers and EGFR Inhibitors
John J. Seman
John J. Seman, Ph.D.
Canget BioTekpharma LLC., Buffalo, NY
Title: Novel portfolio of cancer drugs eliminate tumors and overcome multiple mechanisms of drug resistance