Symposium I: "Medicinal Chemistry and SAR in Hit-to-Lead Development"

Co-Chairman : Guillermo A. Morales, Ph.D.      Thomas E. Smithgall, Ph.D.

Guillermo A. Morales
Guillermo A. Morales, Ph.D., MBA
CEO, Innoventyx, Oro Valley, Arizona
Title: TBA
Benjamin L. Miller
Benjamin L. Miller, Ph.D.
Dean’s Professor of Dermatology, University of Rochester Medical Center, Rochester, NY
Title: Strategies for Targeting Viral RNA with Synthetic Molecules
David H. Thompson
David H. Thompson, Ph.D.
Professor, Department of Chemistry, Purdue University, West Lafayette, IN
Title: TBA
Gokul M. Das
Gokul M. Das, Ph.D.
Associate Professor, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: Drug Repurposing to Target Estrogen Receptor-beta and p53 Interaction: A Novel Therapeutic Strategy against Triple Negative Breast Cancer
Thomas E. Smithgall
Thomas E. Smithgall, Ph.D.
Chair, Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA
Title: Drug Discovery Targeting Src-family Kinases in Acute Myeloid Leukemia
Paul C. Trippier
Paul C. Trippier, Ph.D.
Associate Professor, Department of Pharmaceutical Sciences, University of Nebraska Medical Center Omaha, NE
Title: Multi-functional Small Molecules for Drug Discovery in CLN3 Disease

Symposium II: "Preclinical Drug Discovery for Novel Oncology Therapeutics"

Co-Chairman : Arthur M. Edelman, Ph.D.     David H. Thompson, Ph.D.

Andrei V. Gudkov
Andrei V. Gudkov, Ph.D, Dsci
Garman Family Chair, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: TBA
Xiaodong Cheng
Xiaodong Cheng, Ph.D.
Professor, Department of Integrative Biology & Pharmacology, University of Texas Health Science Center at Houston, Houston, TX
Title: TBA
Fengzhi Li
Fengzhi Li, Ph.D.
Chief Scientist, Dept of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: TBA
Chandra Bartholomeusz
Chandra Bartholomeusz, Ph.D.
Associate Professor, The University of Texas MD Anderson Cancer Center, Houston, TX
Title: TBA
Arthur M. Edelman
Arthur M. Edelman, Ph.D.
Associate Professor, University at Buffalo, State University of New York, NY
Title: Kinases and Cancer, the Curious Case of CaMKK2
Dhyan Chandra
Dhyan Chandra, Ph.D.
Associate Professor, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: Mitochondrial Dysfunction in Cancer
Xinjiang Wang
Xinjiang Wang, Ph.D.
Associate Professor, Dept. of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: TBA

Symposium III: "Target Validation and Enabling Preclinical Technologies"

Co-Chairman : Upinder Singh, M.D.      Stephen A. Duncan, Ph.D.

Larry Sklar
Larry Sklar, Ph.D.
Director, UNM Center for Molecular Discovery, NM
Title: Two Decades of High Throughput Flow Cytometry for Drug Discovery and Repurposing at the University of New Mexico Center for Molecular Discovery
Lisa A. Delouise
Lisa A. Delouise, Ph.D., M.P.D
Associate Professor, University of Rochester Medical Center, Rochester, NY
Title: Microbubble Arrays: A Platform Technology for High-throughput Screening of Single Cells and Tissues
Danielle S.W. Benoit
Danielle S.W. Benoit, Ph.D.
Director, Materials Science Program, University of Rochester, Rochester, NY
Title: ‘Smart’ to Biomimetic Materials: Taking cues from nature to enable RNAi delivery
Stephen A. Duncan
Stephen A. Duncan, Ph.D.
Medical University of South Carolina, Charleston, SC
Title: Using iPSC-derived Hepatocytes as a Platform to Identity Treatments for Metabolic Liver Disease
Upinder Singh
Upinder Singh, M.D.
Chief, Infectious Diseases & Geographic Medicine, Stanford University, Stanford, CA
Title: TBA
Marton Toth
Marton Toth, Ph.D.
Business Development Manager, NemaLife Inc., st., Lubbock, TX
Title: TBA
Elysia Masters
Elysia Masters
University of Rochester, Rochester, NY
Title: A Preclinical Drug Discovery Platform for Novel Antibiotics to Treat Bone Infections

Symposium IV: "Nucleic Acids-Based Therapeutics, Gene Editing and Antiviral Therapeutics"

Co-Chairman : Troels Koch, M.Sc., Ph.D.      Jack M. Sullivan, M.D., Ph.D.

Sterghios A. Moschos
Sterghios A. Moschos, FRSC FIBMS FHEA MRSB
Northumbria University, UK
Title: Resolving Cytosolic Molecular Therapy for Airways Disease
Dean Tang
Dean Tang, Ph.D.
Director, the ET Graduate Program, Roswell Park Comprehensive Cancer Center, Buffalo, NY
Title: TBA
Ergün Sahin
Ergün Sahin, M.D, Ph.D.
Assistant Professor, Baylor College of Medicine, Houston, TX
Title: TBA
Danith H. Ly
Danith H. Ly, Ph.D.
Professor, Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA
Title: Bivalent Recognition: A Novel Approach for Targeting the Secondary and Tertiary Structures of RNA
Ramana V. Davuluri
Ramana V. Davuluri, Ph.D.
Northwestern University - Feinberg School of Medicine, Chicago, IL
Title: Transitioning Novel MerTK Small Molecule Inhibitors into Oncology Clinical Trials
Jack M. Sullivan
Jack M. Sullivan, M.D., Ph.D
Jacobs School of Medicine & Biomedical Sciences, Buffalo, NY
Title: Hammerhead Ribozymes with Protein-Level Catalytic Rates- Revitalizing a Post-Transcriptional Modality for Therapeutic RNA Drug Discovery
Jian Zhu
Jian Zhu, Ph.D.
Associate Professor, Department of Pathology, Ohio State University College of Medicine Columbus, OH
Title: TBA
Michael Shtutman
Michael Shtutman, Ph.D.
Director of Functional Genomics Facility, University of South Carolina, Columbia, SC
Title: TBA

Symposium V: "Cannabinoids and Terpenes Targeting of the Endocannabinoid System"

Co-Chairman : Lisa L. Braun, DC, MS     Eilis Dowd, Ph.D.

Elmar Nurmemmedov
Dvora Namdar, Ph.D.
Senior Research Fellow, Institute of Plant Sciences, ARO, Volcani Center, Israel
Title: TBA
István Katona
István Katona, Ph.D.
Naus Family Chair in Addiction Sciences, Indiana University, Bloomington/Institute of Experimental Medicine, Budapest, Hungary
Title: TBA
Eilis Dowd
Eilis Dowd, Ph.D.
Senior Lecturer in Pharmacology, National University of Ireland, Galway, Ireland
Title: Neuroinflammation in Parkinson’s, and the Therapeutic Potential of Cannabinoids.
Steven Laviolette
Steven Laviolette, Ph.D.
Professor, Department of Anatomy and Cell Biology, University of Western Ontario, Ontario, Canada
Title: TBA
Malliga R. Iyer
Malliga R. Iyer, Ph.D.
Staff Scientist, Director of Medicinal Chemistry Core, NIAAA/NIH, Rockville, MD
Title: Cannabinoid Receptor-based Polypharmacological Approaches to treat Metabolic and Fibrotic Disorders
Paul J. Kenny
Paul J. Kenny, Ph.D.
Director, Experimental Therapeautics Institute, Icahn School of Medicine at Mount Sinai, New York City, NY
Title: TBA
Christopher W. Cunningham
Christopher W. Cunningham, Ph.D.
Director, Center for Structure-Based Drug Design & Development, Mequon, WI
Title: Endocannabinoid Transport Inhibitors as Novel Anxiolytics
David A. Scott
David A. Scott, Ph.D.
Professor, Oral Immunology & Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY
Title: TBA

Symposium VI: "Optimizing Cannabis Cultivars and Products for Medicinal Efficacy"

Co-Chairman : Steve VanDeWalle, MBA     István Katona, Ph.D.

Lakshmi P. Kotra
Lakshmi P. Kotra, Ph.D.
Professor, University of Toronto, and Senior Scientist, University Health Network, Toronto, ON, Canada
Title: Bedside to Bud: Tying the Patient to Medicine
Bernd Markus-Lange
Bernd Markus-Lange, Ph.D.
Washington State University, Pullman, WA
Title: Beyond the High: Intertwined Biochemical Pathways Toward Cannabinoids and Aroma Terpenoids in Cannabis