P-01 Effect of gender and animal species on pharmacokinetic profile in the development of a novel neuropathic drug candidate CPL298 - a 5-HT7 receptor agonist,
presenting by Maria Walczak, Jagiellonian University Medical College, Poland

Co: Authors: Maciej Gawlik¹, Magdalena Smolik¹, Ewa Niedzielska-Andres¹, Adam Hogendorf², Andrzej Bojarski², Mikołaj Matłoka^3
1 Chair and Department of Toxicology, Faculty of Pharmacy Jagiellonian University Medical College, Krakow, Poland
² Department of Medicinal Chemistry Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
³ Celon Pharma S.A., R&D Center, Kielpin, Poland

P-02 Probiotic properties analysis of isolated lactic acid bacteria from milk
Presenting by Alazar Essayas, Assistant professor and researcher, Wollo University, Ethiopia

P-03 Dual-Action Antimicrobial Peptide Mimicking Hydrogels Containing Nitric-Oxide Releasing Functional Groups
Presenting by Samuel Attard, University of New South Wales, Australia

Co: Authors: Samuel T. Attard^1*, Vina Aldilla¹, Mark D. P. Willcox¹ and Naresh Kumar^1
1 University of New South Wales, Australia

P-04: Design, Synthesis, and Biological Evaluation of Some 2-(3-oxo-5,6-diphenyl-1,2,4-triazin-2(3H)-yl)-N-phenylacetamide Hybrids as Multi-Target-Directed Ligands for Alzheimer’s Disease Therapy
Presenting by Digambar Kumar Waiker, Department of Biological Sciences, Purdue University, IN, USA

Co: Authors: Digambar Kumar Waiker^a,c, Vincent Jo. Davisson^b, Sushant Kumar Shrivastava^a
a Department of Pharmaceutical Engineering and Technology, Indian Institute Technology-BHU, Varanasi, India.
^b Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette
^c Department of Biological Sciences, Purdue University, West Lafayette, Indiana

P:05 Pioglitazone ameliorates DOX-induced cognitive impairment by mitigating inflammation, oxidative stress, and apoptosis of hippocampal neurons in rats
Presenting by Ahmad Alhowai, Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Saudi Arabia

P:06 Protective Effect of Galantamine against Doxorubicin-Induced Neurotoxicity
Presenting by Maha Aldubayan, Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Saudi Arabia

Co: Authors: Rawan Alsikhan ¹, Maha Aldubayan ^1*, Ibtesam S Almami ², Ahmad H Alhowail ^1
1 Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah 51452, Al Qassim, Saudi Arabia
² Department of Biology, College of Sciences, Qassim University, Buraydah 51452, Al Qassim, Saudi Arabia

P:07 Invitro antiviral evaluation of fluoro, chloro and bromo hydantoin derivatives against multiple variants of SARS-CoV-2, exhibiting a trend in agreement with computationally derived binding affinities
Presenting by Anushri Pal, Acton Boxborough Regional High School, Acton, MA

Co: Authors: Anushri Pal^1*, Mahendra D. Chordia^2
1Acton Boxborough Regional High School, MA, USA
²Department of Chemistry, University of Virginia, Charlottesville, VA, USA

P:08 AI for drugging hard targets
Presenting by Naeyma Islam, Mayo Clinic, Jacksonville, FL

P:09 Small Molecule Inhibitors for Directed Targeting of BET/BRD4 Extra-Terminal Domain in Multiple Myeloma
Presenting by Shoshanah M. Holub, The Ohio State University, Columbus, OH

Co: Authors: Shoshanah M. Holub^1*, Luisa Tomasello¹ , Enming Xing² , Pui-Kai Li² , Kristine E. Yoder¹ , Ross C. Larue^1
1Department of Biology and Cancer Genetics, The Ohio State University, Columbus, OH, USA;
²Medicinal Chemistry and Pharmacognosy, The Ohio State University, Columbus, OH, USA

P-10 Identifying Realistic Quantum Mechanics-Based Conformations and Creating High-Quality Datasets for Drug Repurposing
Presenting by Laszlo Fusti-Molnar, QuantumFuture Scientific Software LLC, Buda, TX

P:11 Molecular Insights into Traditional Chinese Medicine Compounds for the Treatment of Ischemic Stroke
Presenting by Yuhan Li, Macau University of Science and Technology, China

Co: Authors: Li Yuhan^1*, Wu Wanyu¹, Peng Yutong¹, Zheng Wuyan
¹Faculty of Medicine, Macau University of Science and Technology, Macau

P:12 KMP01D inhibits Inflammatory Responses in Immune Cells from Patients with Colorectal Cancer: Results from an ex-vivo Preclinical Study
Presenting by Martin Gasser, Brigham and Woman’s Hospital, Dept. of Medicine, Genetics, Harvard Medical School, Boston, MA

Co: Authors: Martin Gasser^*1, Reinhard Lissner², Georg Wolz³, and Ana Maria Waaga-Gasser^4
1 Brigham and Woman’s Hospital, Dept. of Medicine, Genetics, Harvard Medical School, Boston, USA
² em. Professor Univ. of Frankfurt, Gönz, Germany
³ Dr. Wolz Zell GmbH, Geisenheim, Germany
⁴ Brigham and Woman’s Hospital, Renal Division, Harvard Medical School, Boston, USA

P:13 Translocation of Complex Macromolecules Across the Intestinal Epithelial Barrier
Presenting by Kyungbo Kim, BioMed X Institute, Germany

P:14 Targeting SIRT1/AMPK/Nrf2/NF-кB by sitagliptin protects against oxidative stress-mediated ER stress and inflammation during ANIT-induced cholestatic liver injury
Presenting by Nabil A. Alhakamy, King Abdulaziz University, Saudi Arabia

Co: Authors: Rami M. Mosaoa¹, Mohammed W. Al-Rabia¹, Hani Z. Asfour¹, Nabil A. Alhakamy¹, Rasha A. Mansouri¹, Dina S. El-Agamy¹, Wesam H. Abdulaal², Gamal A. Mohamed¹, Sabrin R.M. Ibrahim¹, Mahmoud Elshal^3
1 King Abdulaziz University, Saudi Arabia;
² Mansoura University, Egypt;
³ Batterjee Medical College, Saudi Arabia